2. Signaling Pathways
  3. Apoptosis
  4. Caspase
  5. Caspase 5 Isoform
  6. Caspase 5 Activator

Caspase 5 Activator

Caspase 5 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-N8508
    Myrothecine A
    		Activator
    Myrothecine A is a trichothecene mycotoxin found in M. roridum. Myrothecine A induces apoptosis, promotes the cytochrome c release, PARP-cleavage and phosphorylation of JNK, increases Bax and cleaved caspase-3, -5, and -8 levels. Myrothecine A has anticancer activities and promotes the maturation of DC cells in the microenvironment. Myrothecine A inhibits proliferation of A549, MCF-7, HepG2, and SMMC-7721 cancer cells with IC50s of 95, 70, 60, and 25 µM, respectively.