2. Signaling Pathways
  3. GPCR/G Protein
  4. EBI2/GPR183
  5. EBI2/GPR183 Agonist

EBI2/GPR183 Agonist

EBI2/GPR183 Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-113962
    7α,25-Dihydroxycholesterol
    		Agonist ≥99.0%
    7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells.