2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. G-quadruplex
  5. G-quadruplex Ligand

G-quadruplex Ligand

G-quadruplex Ligands (2):

Cat. No. Product Name Effect Purity
  • HY-170814
    G-quadruplex ligand 3
    		Ligand
    G-quadruplex ligand 3 (Compound 16) is a G-quadruplex ligand with anticancer effects that chelate iron. G-quadruplex ligand 3 stabilizes G-quadruplexes in human leukemia Jurkat cells. G-quadruplex ligand 3 localizes in the cell nucleus, serving as a fluorescent nuclear tracer for the labile iron pool.
  • HY-145748
    SYUIQ-5
    		Ligand
    SYUIQ-5 is a G-quadruplex ligand. SYUIQ-5 stabilizes G-quadruplex and induce senescence. SYUIQ-5 inhibits c-myc gene promoter activity. SYUIQ-5 induces cancer cells autophagy by triggering telomere damage through TRF2 delocalization from telomeres.