2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. G-quadruplex
  5. G-quadruplex Inhibitor

G-quadruplex Inhibitor

G-quadruplex Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-108477
    TMPyP4 tosylate
    		Inhibitor ≥98.0%
    TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand. TMPyP4 tosylate inhibits the interaction between G-quadruplexes and IGF-1. TMPyP4 tosylate is a telomerase inhibitor and inhibits cancer cells proliferation. TMPyP4 tosylate is also a stabilizer of nucleic acid secondary structure and an acetylcholinesterase inhibitor. Besides, TMPyP4 tosylate has antiviral activity against SARS-CoV-2.
  • HY-15594A
    Phen-DC3 Trifluoromethanesulfonate
    		Inhibitor 98.99%
    Phen-DC3 Trifluoromethanesulfonate is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.
  • HY-16967
    MM41
    		Inhibitor 99.92%
    MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC50 value of <10 nM.