1. Signaling Pathways
  2. Cytoskeleton
  3. Integrin
  4. Integrin Activator

Integrin Activator

Integrin Activators (3):

Cat. No. Product Name Effect Purity
  • HY-P3523
    KGDS
    Activator
    KGDS is synthetic peptides, targeting integrin GPIIb-IIIa located on the membrane of human activated platelets. Amino acid sequence: Lys-Gly-Asp-Ser.
  • HY-P5812
    IDR 1002
    Activator
    IDR-1002 is an anti-infective peptide that enhances the ability of human monocytes to migrate toward chemokines on fibronectin. IDR-1002 also induces adhesion and activation of β1-integrin, a mechanism that promotes monocyte recruitment.
  • HY-W654264
    2-Methylbutyrylcarnitine chloride
    Activator
    2-Methylbutyrylcarnitine (chloride) is a gut microbial metabolite which binds to integrin α2β1 in platelets, potentiating cytosolic phospholipase A2 (cPLA2) activation and platelet hyperresponsiveness. 2-Methylbutyrylcarnitine (chloride) enhances platelet hyperreactivity and thrombus formation in mice. 2-Methylbutyrylcarnitine (chloride) is a branched-chain acylcarnitine.