2-Methylbutyrylcarnitine chloride

Cat. No.: HY-W654264: FAQs
Data Sheet Handling Instructions

Molarity Calculator

2-Methylbutyrylcarnitine (chloride) is a gut microbial metabolite which binds to integrin α2β1 in platelets, potentiating cytosolic phospholipase A2 (cPLA2) activation and platelet hyperresponsiveness. 2-Methylbutyrylcarnitine (chloride) enhances platelet hyperreactivity and thrombus formation in mice. 2-Methylbutyrylcarnitine (chloride) is a branched-chain acylcarnitine.

For research use only. We do not sell to patients.

2-Methylbutyrylcarnitine chloride Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 75	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 2-Methylbutyrylcarnitine chloride:

2-Methylbutyrylcarnitine Get quote

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•Related Screening Libraries:

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View All Integrin Isoform Specific Products:

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

281.78

Formula

C₁₂H₂₄ClNO₄

Appearance

Solid

SMILES

CCC(C)C(O[C@H](CC(O)=O)C[N+](C)(C)C)=O.[Cl-]

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (354.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5489 mL	17.7443 mL	35.4887 mL
5 mM	0.7098 mL	3.5489 mL	7.0977 mL
10 mM	0.3549 mL	1.7744 mL	3.5489 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Huang K, et al. Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin α2β1. Cell Metab. 2024 Mar 5;36(3):598-616.e9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5489 mL	17.7443 mL	35.4887 mL	88.7217 mL
	5 mM	0.7098 mL	3.5489 mL	7.0977 mL	17.7443 mL
	10 mM	0.3549 mL	1.7744 mL	3.5489 mL	8.8722 mL
	15 mM	0.2366 mL	1.1830 mL	2.3659 mL	5.9148 mL
	20 mM	0.1774 mL	0.8872 mL	1.7744 mL	4.4361 mL
	25 mM	0.1420 mL	0.7098 mL	1.4195 mL	3.5489 mL
	30 mM	0.1183 mL	0.5915 mL	1.1830 mL	2.9574 mL
	40 mM	0.0887 mL	0.4436 mL	0.8872 mL	2.2180 mL
	50 mM	0.0710 mL	0.3549 mL	0.7098 mL	1.7744 mL
	60 mM	0.0591 mL	0.2957 mL	0.5915 mL	1.4787 mL
	80 mM	0.0444 mL	0.2218 mL	0.4436 mL	1.1090 mL
	100 mM	0.0355 mL	0.1774 mL	0.3549 mL	0.8872 mL