2. Signaling Pathways
  3. Cytoskeleton
  4. Integrin
  5. Integrin Modulator

Integrin Modulator

Integrin Isoform Comparison

Integrin Modulators (5):

Cat. No. Product Name Effect Purity
  • HY-P3160
    Fibronectin
    		Modulator
    Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans.
  • HY-P0031
    Cyclo(RADfK)
    		Modulator
    Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.
  • HY-48959
    α7β1 integrin modulator-1
    		Modulator ≥98.0%
    α7β1 integrin modulator-1 is a potent α7β1 integrin modulator. α7β1 integrin modulator-1 has the potential for the research of muscular dystrophy.
  • HY-P10783
    BGC0222
    		Modulator
    BGC0222 is a novel prodrug of Irinotecan (HY-16562). BGC0222, as a PEG-cRGD-conjugated Irinotecan (HY-16562) derivative, could slowly and steadily release Irinotecan (HY-16562). BGC0222 binds to αVβ3 with IC50 values of 4.25 μM (αVβ3) and 58.7 μM (αVβ5). BGC0222 possesses the property of inducing neovascularization. BGC0222 exhibits good antiproliferation activity in many tumors.
  • HY-P6438
    Alkyne-cRGD
    		Modulator
    Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction.