2. Cytoskeleton
  3. Integrin
  4. Fibronectin

Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans.

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Fibronectin Chemical Structure

Fibronectin Chemical Structure

CAS No. : 86088-83-7

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Based on 2 publication(s) in Google Scholar

Fibronectin Related Antibodies

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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Description

Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans[1].

In Vitro

Fibronectin (FN) is a glycoprotein present in blood as well as in cells. While Fibronectin (FN) in blood has many functions, its primary role is to promote wound repair following injury[1].
Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans) [2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fibronectin Related Antibodies
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Appearance

Solid

Color

White to off-white

SMILES

[Fibronectin]
Structure Classification
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Room temperature in continental US; may vary elsewhere.
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Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

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In Vitro: 

H2O : 8.33 mg/mL (ultrasonic and adjust pH to 7 with NaOH)

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Purity & Documentation

Purity: ≥97.0%

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Fibronectin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fibronectin86088-83-7IntegrintissueinjuryinflammationtraumaatherosclerosisInhibitorinhibitorinhibit

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