2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-10 Isoform
  6. IL-10 Activator

IL-10 Activator

IL-10 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-122586
    BRD6989
    		Activator 99.56%
    BRD6989, an analog of the natural product cortistatin A (dCA), inhibits CDK8 and upregulates IL-10. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes.