Isocitrate Dehydrogenase (IDH) Inhibitors

IDH1

IDH2

Isocitrate Dehydrogenase (IDH) Inhibitors

Product Name	IDH1	IDH2	Purity
Vorasidenib	IDH1	IDH2	99.87%
Enasidenib		IDH2	99.90%
AGI-6780		IDH2	98.87%
GSK864	IDH1		99.91%
TQ05310		IDH2-R140Q, IC₅₀: 136.9 nM
AGI-5198	IDH1		99.77%
BAY-1436032	IDH1		99.48%
Enasidenib mesylate		IDH2	99.85%
Olutasidenib	IDH1		99.30%
IDH1 Inhibitor 2	IDH1		99.40%
Mutant IDH1-IN-1	IDH1		99.43%
(R,R)-GSK321	IDH1		99.31%
(S,R)-GSK321	IDH1		98.78%
Mutant IDH1-IN-2	IDH1		98.50%
LY3410738	IDH1	IDH2
IDH1 Inhibitor 7	IDH1, IC₅₀: <100 nM		99.46%
Safusidenib	IDH1
TC-E 5008	R132H IDH1, Ki: 190 nM R132C IDH1, Ki: 120 nM WT IDH1, Ki: 12.3 μM
Mutant IDH1/NAMPT-IN-1	IDH1, IC₅₀: 14.93 nM
IHMT-IDH1-053	R132H IDH1, IC₅₀: 4.7 μM
BRD2879	R132H IDH1, IC₅₀: 0.05 μM R132C IDH1, IC₅₀: 2.5 μM IDH1 wt, IC₅₀: >20 μM	IDH2-R140Q, IC₅₀: >20 μM
IDH1 Inhibitor 9	R132H IDH1, IC₅₀: 124.4 nM R132C IDH1, IC₅₀: 95.7 nM

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