2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. JNK
  5. JNK Isoform
  6. JNK Agonist

JNK Agonist

JNK Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-173188
    EGFR-IN-154
    		Agonist
    EGFR-IN-154 (compound 4c) is an EGFR inhibitor with EC50 values of 0.16 μM, 21.73 μM and 41.56 μM against EGFR Del19, EGFR WT and EGFR L858R, respectively. EGFR-IN-154 shows anticancer activity on various cance cell lines. EGFR-IN-154 induces mitochondrial apoptosis, and decreases pERK1/2 and pAkt levels, but increases pJNK and pp38 levels.
  • HY-103074
    GSK2226649A
    		Agonist
    GSK2226649A (compound 2) is a novel activator of satellite cell proliferation and enhanced repair of damaged muscle.