2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. JNK
  5. JNK3 Isoform
  6. JNK3 Activator

JNK3 Activator

JNK3 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-N13294
    Cernuumolide J
    		Activator
    Cernuumolide J (TMJ-105) is an JAK2/STAT3 inhibitor. Cernuumolide J induces G2/M phase arrest and apoptosis in HEL leukemia cells by downregulating the phosphorylation of JAK2, STAT3, and Erk, and activating the phosphorylation of JNK and p38 MAPK. Cernuumolide J inhibits HEL leukemia cell growth in a time- and concentration-dependent manner, with an IC50 value of 1.79 μM. Cernuumolide J can be used for research in the field of anti-cancer therapy.