2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. KLF
  5. KLF Activator

KLF Activator

KLF Activator (1):

Cat. No. Product Name Effect Purity
  • HY-16291
    APTO-253
    		Activator 98.81%
    APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor. APTO-253 has antiarthritic activity.