2. Signaling Pathways
  3. PROTAC
  4. Ligands for E3 Ligase
  5. MDM2 Isoform

MDM2

 

MDM2 Related Products (5):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-128837
    Nutlin carboxylic acid 2249750-27-2 98.63%
    Nutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTAC.
    Nutlin carboxylic acid
  • HY-128836
    (4R,5S)-Nutlin carboxylic acid 2306390-08-7
    (4R,5S)-Nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs.
    (4R,5S)-Nutlin carboxylic acid
  • HY-P5930
    HOXB7 8–25
    HOXB7 8–25 (MDM2 32-46) is an MDM2-derived peptide epitope and can elicit antigen-specifc and tumor-reactive CD4+ T cell responses.
    HOXB7 8–25
  • HY-148106
    MEL23 642072-49-9
    MEL23 is a MDM2 E3 ligase inhibitor that blocks the E3 ligase activity of the MDM2-MDMX complex. MEL23 inhibits Mdm2 and p53 ubiquitination in cells, reduce viability of cells with wild-type p53. MEL23 stabilizes MDM2 via a mechanism independent of p53 transcription.
    MEL23
  • HY-168280
    AS1411-C4-VH032
    AS1411-C4-VH032 (AS1411-VH032) promotes tumor-selective degradation of MDM2, leading to tumor shrinkage without detectable toxicity.
    AS1411-C4-VH032