2. PROTAC
  3. Ligands for E3 Ligase
  4. (4R,5S)-Nutlin carboxylic acid

(4R,5S)-Nutlin carboxylic acid  (Synonyms: MDM2 ligand 2; E3 ligase Ligand 15)

Cat. No.: HY-128836
Data Sheet Handling Instructions Technical Support

(4R,5S)-Nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

(4R,5S)-Nutlin carboxylic acid Chemical Structure

(4R,5S)-Nutlin carboxylic acid Chemical Structure

CAS No. : 2306390-08-7

Size Price Stock Quantity
5 mg USD 112 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
10 mg USD 179 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
25 mg USD 359 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 mg USD 609 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 mg USD 974 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks

Get it by April 4 for select sizes. Order within 15 hrs 3 mins.

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Based on 1 publication(s) in Google Scholar

Other Forms of (4R,5S)-Nutlin carboxylic acid:

(4R,5S)-Nutlin carboxylic acid Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1

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Description

(4R,5S)-Nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs[1].

IC50 & Target

MDM2

 

Molecular Weight

639.53

Formula

C32H32Cl2N4O6
CAS No.
SMILES

O=C1N(CC(O)=O)CCN(C(N2[C@@H](C3=CC=C(Cl)C=C3)[C@@H](C4=CC=C(Cl)C=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(4R,5S)-Nutlin carboxylic acid Related Classifications

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(4R,5S)-Nutlin carboxylic acid2306390-08-7MDM2 ligand 2 E3 ligase Ligand 15Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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