1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0243R
    Theaflavin (Standard)
    Theaflavin (Standard) is the analytical standard of Theaflavin. This product is intended for research and analytical applications. Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.
    Theaflavin (Standard)
  • HY-19495
    OT-730
    OT-730 is an innovative selective beta-blocker prodrug designed for research into ocular diseases.
    OT-730
  • HY-N7063S
    Nerol-d2
    Nerol-d2 is deuterated labeled Octanal (HY-N8015). Octanal is an aromatic aldehyde, with antioxidant and antimicrobial activities. Octanal shows cytotoxicity against Hela cells.
    Nerol-d<sub>2</sub>
  • HY-124151R
    Adenosine-2'-monophosphate (Standard)
    Bisphenol A diglycidyl ether (Standard) is the analytical standard of Bisphenol A diglycidyl ether. This product is intended for research and analytical applications. Bisphenol A diglycidyl ether is used as a stabilizer and embedding agent.
    Adenosine-2'-monophosphate (Standard)
  • HY-B0661S
    Tamsulosin-d4
    Tamsulosin-d4 ((R)-(-)-YM12617 (free base)-d4) is deuterium labeled Tamsulosin. Tamsulosin ((R)-(-)-YM12617 free base) is an inhibitor of α1-adrenergic receptor. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth in animal models.
    Tamsulosin-d<sub>4</sub>
  • HY-N1500S1
    Pulegone-d8
    Pulegone-d8 is deuterated labeled Tetracycline (HY-A0107). Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections.
    Pulegone-d<sub>8</sub>
  • HY-118774R
    Propofol β-D-glucuronide (Standard)
    Propofol β-D-glucuronide (Standard) is the analytical standard of Propofol β-D-glucuronide. This product is intended for research and analytical applications. Propofol β-D-glucuronide is a metabolite of Propofol sulfate and can be used for diagnosis to distinguish colorectal cancer from healthy individuals.
    Propofol β-D-glucuronide (Standard)
  • HY-N0097S4
    Guanosine-13C10
    Guanosine-13C10 is the 13C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.
    Guanosine-<sup>13</sup>C<sub>10</sub>
  • HY-138107
    Arimistane
    Arimistane is a metabolite of 7-oxo-DHEA and can be used as a diagnostic marker of 7-oxo-DHEA administration.Arimistane is a metabolite of 7-oxo-DHEA and can be used as a diagnostic marker of 7-oxo-DHEA administration.
    Arimistane
  • HY-18252S2
    Avanafil-d4
    Modulator
    Avanafil-d4 (TA1790-d4) is deuterium-labeled Avanafil (HY-18252).
    Avanafil-d<sub>4</sub>
  • HY-W591060
    Bis(bipyridine)-(5-aminophenanthroline)
    Bis(bipyridine)-(5-aminophenanthroline) is an organic catalyst with photocatalytic activity. The use of Bis(bipyridine)-(5-aminophenanthroline) in hematology involves its use as a stain for tissue diagnosis. Bis(bipyridine)-(5-aminophenanthroline) can be used as a transition metal catalyst in catalytic reactions. Bis(bipyridine)-(5-aminophenanthroline) has also been used in the study of ruthenium catalysts.
    Bis(bipyridine)-(5-aminophenanthroline)
  • HY-B0660R
    Eicosapentaenoic Acid (Standard)
    Eicosapentaenoic Acid (Standard) is the analytical standard of Eicosapentaenoic Acid. This product is intended for research and analytical applications. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation.
    Eicosapentaenoic Acid (Standard)
  • HY-113517R
    Normetanephrine (Standard)
    Normetanephrine (Standard) is the analytical standard of Normetanephrine. This product is intended for research and analytical applications. Normetanephrine is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Hypertension.
    Normetanephrine (Standard)
  • HY-124399
    N-Octadecyl-N'-propyl-sulfamide
    Peroxisome proliferator-activated receptors (PPARs) play an important role in regulating lipid and glucose metabolism, and oleoylethanolamide (OEA) is a natural ligand for PPARα. N-Octadecyl-N'-propyl-sulfamide is an analog of OEA and a potent activator of PPARα, with selective binding affinity for PPARα (EC50=100 nM, compared to 120 nM for OEA). N-Octadecyl-N'-propyl-sulfamide (10 mg/kg; ip) inhibits food intake and reduces body weight gain in rats. At a dose of 1 mg/kg, N-Octadecyl-N'-propyl-sulfamide induces satiety, thereby reducing food intake, body weight, and plasma triglyceride concentrations in free-feeding Wistar rats and obese Zucker (fa/fa) rats.
    N-Octadecyl-N'-propyl-sulfamide
  • HY-N13017
    Bhimanone
    Bhimanone is a bioinactive tetralone, which can be isolated from Streptomyces sp..
    Bhimanone
  • HY-N7736
    Furan fatty acid F5
    12,15-epoxy-13-methyl-12,14-Eicosadienoic acid is a furan fatty acid originally isolated from northern pike (E. lucius).1 Levels of 12,15-epoxy-13-methyl-12,14-eicosadienoic acid are increased in the liver of starving cod.
    Furan fatty acid F5
  • HY-131306A
    Δ2-trans-Hexadecenoic acid
    Δ2-trans-Hexadecenoic acid is a trans fatty acid isolated from the seed oil of Aster tataricus (Thunb.).
    Δ2-trans-Hexadecenoic acid
  • HY-168778
    (±)-Δ7-Mesembrenone
    (±)-Δ7-Mesembrenone is a mesembrine-type alkaloid which can be extracted from various Sceletium.
    (±)-Δ7-Mesembrenone
  • HY-120599A
    Sabizabulin hydrochloride
    Sabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects.
    Sabizabulin hydrochloride
  • HY-Y0801R
    2,6-Dihydroxybenzoic acid (Standard)
    2,6-Dihydroxybenzoic acid (Standard)
Cat. No. Product Name / Synonyms Application Reactivity