2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. N-myristoyltransferase

N-myristoyltransferase

NMT

 

N-myristoyltransferase Related Products (2):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-147308
    PCLX-001
    		Inhibitor 99.05%
    PCLX-001 is an orally acitve, small-molecule, dual N-myristoyltransferase (NMT) inhibitor, with IC50s of 5 nM (NMT1) and 8 nM (NMT2), respectively. PCLX-001 can induce cell apoptosis, has anti-cancer activity, inhibits early B cell receptor (BCR) signaling, and can be used to study malignant lymphoma.
    PCLX-001
  • HY-164285
    MYX1715
    		Inhibitor 98.31%
    MYX1715 is an inhibitor of N-Myristoyltransferase (NMT) with a KD value of 0.09 nM. MYX1715 inhibits the proliferation of LU0884 and LU2511 with IC50 values of 44 nM and 9 nM. MYX1715 exhibits antitumor efficacy against neuroblastoma and gastric cancer in mouse models. MYX1715 can be used as ADC toxin.
    MYX1715