2. Signaling Pathways
  3. NF-κB
  4. NF-κB
  5. c-Rel Isoform

c-Rel

 

c-Rel Related Products (2):

Cat. No. Product Name Effect Purity
  • HY-125864
    Fibrinogen (Bovine)
    		Activator
    Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases.
  • HY-124179
    IT-901
    		Inhibitor ≥99.0%
    IT-901 is an orally active and potent NF-κB subunit c-Rel inhibitor with an IC50 of 0.1 µM, 3 μM for NF-κB DNA binding and c-Rel DNA binding, respectively. IT-901, a bioactive naphthalenethiobarbiturate derivative, has the potential for human lymphoid tumors and ameliorate graft-versus-host disease (GVHD).