NTR1

NTR1 (neurotensin receptor 1) belongs to the large superfamily of G-protein coupled receptors and is considered a class-A GPCR. NTSR1 mediates multiple biological processes through modulation by neurotensin, such as low blood pressure, high blood sugar, low body temperature, antinociception, anti-neuronal damage and regulation of intestinal motility and secretion.

NTR1 Agonists (2)
NTR1 Modulator (1)

NTR1 Related Products (3):

By Effects:	Agonists (2) Modulator (1)

Cat. No.	Product Name	Effect	Purity

HY-P0251

Neurotensin(8-13)	Agonist	99.95%
Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.

HY-125880

SBI-553	Modulator	99.86%
SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC₅₀ of 0.34 μM.

HY-16639

ML314	Agonist	99.52%
ML314 is a potent molecule agonist of NTR1 (EC₅₀ = 1.9 μM); showed good selectivity against NTR2 and GPR35, but does not stimulate Ca²⁺ mobilization.

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