2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. PDGFR
  5. PDGFR Chemical

PDGFR Chemical

PDGFR Isoform Comparison

PDGFR Chemical (1):

Cat. No. Product Name Effect Purity
  • HY-160053
    Gint4.T aptamer sodium
    		Chemical
    Gint4.T aptamer sodium is a nuclease-resistant RNA aptamer-based antagonist targeting platelet-derived growth factor receptor beta (PDGFRβ) (Kd: 9.6 nM). Gint4.T aptamer sodium inhibits PDGFRβ heterodimerization and EGFR transactivation. It can significantly inhibit cell migration and proliferation, induce differentiation and prevent tumor growth in vivo. Gint4.T aptamer sodium specifically inhibits PDGFRβ-mediated tropism of mesenchymal stem cells (MSCs) toward the tumor microenvironment.