1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. PDGFR
  4. PDGFR Inhibitors

PDGFR Inhibitors

PDGFR

PDGFRβ

PDGFRα

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

PDGFR Inhibitors & Modulators
Product Name PDGFR PDGFRβ PDGFRα Purity
Lenvatinib  
PDGFRβ, IC50: 39 nM
PDGFRα, IC50: 51 nM
99.75%
Nintedanib  
PDGFRβ, IC50: 65 nM
PDGFRα, IC50: 59 nM
99.94%
Regorafenib  
PDGFRβ, IC50: 22 nM
  99.93%
Sunitinib  
PDGFRβ, IC50: 2 nM
  99.04%
Multi-kinase inhibitor 3  
PDGFR-β, IC50: 1.15 nM
PDGFRα, IC50: 0.22 nM
WQ-C-401  
PDGFRβ, EC50: 5.8 nM
PDGFRα, EC50: 3.5 nM
Ponatinib    
PDGFRα, IC50: 1.1 nM
99.67%
Axitinib  
PDGFRβ, IC50: 1.6 nM
  99.94%
Pazopanib  
PDGFRβ, IC50: 84 nM
  99.91%
SU 5402  
PDGFRβ, IC50: 510 nM
  99.86%
Nintedanib esylate  
PDGFRβ, IC50: 65 nM
PDGFRα, IC50: 59 nM
99.96%
CP-673451  
PDGFRβ, IC50: 1 nM
PDGFRα, IC50: 10 nM
99.69%
Lenvatinib mesylate  
PDGFRβ, IC50: 39 nM
PDGFRα, IC50: 51 nM
99.86%
Crenolanib  
PDGFRβ, Kd: 3.2 nM
PDGFRα, Kd: 2.1 nM
99.68%
Ripretinib    
PDGFRA
98.90%
Sunitinib Malate  
PDGFRβ, IC50: 2 nM
  99.91%
Linifanib  
PDGFRβ, IC50: 66 nM
  99.28%
Cediranib  
PDGFRβ, IC50: 5 nM
PDGFRα, IC50: 36 nM
99.58%
Dovitinib  
PDGFRβ, IC50: 27 nM
PDGFRα, IC50: 210 nM
99.88%
Pazopanib Hydrochloride  
PDGFRβ, IC50: 84 nM
  99.99%
Regorafenib monohydrate  
PDGFRβ, IC50: 22 nM
  99.96%
CHIR-124
PDGFR, IC50: 6.6 nM
    99.05%
Ponatinib hydrochloride    
PDGFRα, IC50: 1.1 nM
99.55%
Regorafenib Hydrochloride  
PDGFRβ, IC50: 22 nM
  99.58%
Amuvatinib    
PDGFRαV561D, IC50: 40 nM
PDGFRαD842V, IC50: 81 nM
99.47%
SU14813  
PDGFRβ, IC50: 4 nM
  99.63%
Orantinib  
PDGFRβ, Ki: 8 nM
  99.21%
PP121
PDGFR, IC50: 2 nM
    98.67%
Telatinib    
PDGFRα, IC50: 15 nM
99.60%
Ilorasertib hydrochloride  
PDGFRβ, IC50: 13 nM
PDGFRα, IC50: 11 nM
98.48%
ENMD-2076    
PDGFRα, IC50: 56.4 nM
99.12%
Tyrphostin AG1296  
PDGFRβ
PDGFRα
99.69%
JNJ-10198409  
PDGFRβ, IC50: 4.2 nM
PDGFRα, IC50: 45 nM
99.57%
TAK-593  
PDGFRβ, IC50: 13 nM
PDGFRα, IC50: 4.3 nM
PDGFRαV561D, IC50: 1 nM
99.66%
Toceranib  
PDGFRβ, Ki: 5 nM
 
Cediranib maleate  
PDGFRβ, IC50: 5 nM
PDGFRα, IC50: 36 nM
99.95%
Tandutinib
PDGFR, IC50: 0.2 μM
    99.48%
SU4312
PDGFR
    99.76%
Famitinib  
PDGFRβ, IC50: 6.6 nM
  98.43%
Seralutinib  
PDGFRβ
PDGFRα
99.94%
PP58
PDGFR
    99.75%
PDGFRα kinase inhibitor 1  
PDGFRβ, IC50: 6115 nM
PDGFRα, IC50: 132 nM
99.78%
Chiauranib  
PDGFRβ, IC50: 93 nM
PDGFRα, IC50: 1 nM
99.28%
SU16f
PDGFR2, IC50: 140 nM
PDGFR1, IC50: 2.29 μM
PDGFRβ, IC50: 10 nM
  99.09%
Methylnissolin
PDGFR, IC50: 10 μM
    99.86%
Toceranib phosphate  
PDGFRβ, Ki: 5 nM
  98.54%
SU14813 maleate  
PDGFRβ, IC50: 4 nM
  99.04%
PD-161570
PDGFR, IC50: 310 nM
PDGFRβ, IC50: 262 nM
  99.82%
Tovetumab    
PDGFRα
99.49%
TG 100572 Hydrochloride  
PDGFRβ, IC50: 13 nM
  98.96%
JI-101  
PDGFRβ
  99.78%
ENMD-2076 Tartrate    
PDGFRα, IC50: 56.4 nM
99.42%
TG 100801  
PDGFRβ, IC50: 13 nM
  98.61%
Zeteletinib
PDGFR2
    99.06%
XL 999    
PDGFRα, IC50: 4 nM
99.34%
Flumatinib mesylate  
PDGFRβ, IC50: 307.6 nM
  99.87%
AZD2932  
PDGFRβ, IC50: 4 nM
  99.04%
Dovitinib lactate  
PDGFRβ, IC50: 210 nM
PDGFRα, IC50: 27 nM
99.75%
(Z)-Orantinib  
PDGFRβ, IC50: 0.008 μM
  99.44%
Tandutinib hydrochloride
PDGFR, IC50: 0.2 μM
    99.78%
PD-089828  
PDGFR-β, IC50: 1.76 μM
PDGFR-β, Ki: 2.38 μM
  98.07%
Multi-kinase inhibitor 1
PDGFR
    99.34%
Hypothemycin  
PDGFRβ, Ki: 900 nM
PDGFRα, Ki: 1.5 μM
≥98.0%
PDGFRα kinase inhibitor 2
PDGFR, IC50: 1.39 μM
    98.95%
AC710  
PDGFRβ, Kd: 1 nM
PDGFRα, Kd: 1.3 nM
99.13%
AXL-IN-13  
PDGFRβ, Kd: 2.3 nM
  98.03%
HG-7-85-01    
PDGFRα, IC50: 440 nM
99.94%
Ilorasertib  
PDGFRβ, IC50: 13 nM
PDGFRα, IC50: 11 nM
99.86%
Telatinib mesylate    
PDGFRα, IC50: 15 nM
99.74%
GZD856 formic  
PDGFRβ, IC50: 136.6 nM
PDGFRα, IC50: 68.6 nM
98.06%
KG5  
PDGFRβ, Kd: 520 nM
PDGFRα, Kd: 300 nM
99.79%
Tyrphostin AG1433  
PDGFRβ, IC50: 5 μM
  99.08%
NVP-ACC789  
PDGFR-β, IC50: 1.4 μM
  99.52%
AG 370
PDGFR, IC50: 20 μM
   
Sunitinib-d10  
PDGFRβ, IC50: 2 nM
  99.89%
Ponatinib-d8    
PDGFRα, IC50: 1.1 nM
99.91%
TG 100572  
PDGFRβ, IC50: 13 nM
 
Dovitinib lactate hydrate  
PDGFRβ, IC50: 210 nM
PDGFRα, IC50: 27 nM
Regorafenib mesylate  
PDGFRβ, IC50: 22 ± 3 nM
 
GZD856  
PDGFRβ, IC50: 136.6 nM
PDGFRα, IC50: 68.6 nM
Amuvatinib hydrochloride    
PDGFRαV561D, IC50: 40 nM
PDGFRαD842V, IC50: 81 nM
Zeteletinib hemiadipate
PDGFR2
   
Famitinib malate  
PDGFRβ, IC50: 6.6 nM
 
SU 5402 (GMP)  
PDGFRβ, IC50: 510 nM
 
Multi-kinase-IN-1    
PDGFRα, IC50: 0.384 μM
Ki11502  
PDGFRβ, IC50: <10 nM
PDGFRα, IC50: <10 nM
99.30%
Multi-kinase inhibitor 4  
PDGFRβ, IC50: 0.89 nM
PDGFRα, IC50: 0.18 nM
SA-PA  
PDGFR-β
 
Multi-kinase-IN-2  
PDGFRβ, IC50: 9.9 ± 0.7 nM
PDGFRα, IC50: 7.0 ± 0.1 nM
Multi-kinase-IN-3  
PDGFRβ, IC50: 55 ± 2.6 nM
 
Multi-kinase-IN-5
PDGFR
   
BMS-605541  
PDGFR-β, IC50: 200 nM
  99.57%
IHMT-TRK-284  
PDGFRβ, IC50: 95.7 nM
PDGFRα, IC50: 24.2 nM
Henatinib  
PDGFRβ
PDGFRα
TG 100801 Hydrochloride  
PDGFRβ, IC50: 13 nM
 
VEGFR-2-IN-44  
PDGFR-β, IC50: 920 nM
 
SU-4313
PDGFR, IC50: 14.5 μM
   
AC710 Mesylate  
PDGFRβ, Kd: 1 nM
PDGFRα, Kd: 1.3 nM