2. Signaling Pathways
  3. PI3K/Akt/mTOR
  4. PIKfyve
  5. PIKfyve Degrader

PIKfyve Degrader

PIKfyve Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-155994
    PIK5-12d
    		Degrader 99.90%
    PIK5-12d is a PROTAC PIKfyve degrader (DC50: 1.48 nM). PIK5-12d induces massive cytoplasmic vacuolization and blocks autophagic flux in multiple prostate cancer cells. PIK5-12d inhibits prostate cancer cell proliferation. PIK5-12d has anti-tumor activity.