2. Signaling Pathways
  3. Anti-infection
  4. SARS-CoV
  5. SARS-CoV Control

SARS-CoV Control

SARS-CoV Controls (5):

Cat. No. Product Name Effect Purity
  • HY-B1370E
    (R)-Hydroxychloroquine phosphate
    		Control
    (R)-Hydroxychloroquine ((R)-HCQ) phosphate is a (R)-isomer of Hydroxychloroquine (HY-W031727). (R)-Hydroxychloroquine inhibits the insulin metabolizing enzyme of cytosolic fraction of liver homogenates in healthy and diabetic rats.
  • HY-100211A
    (R)-TAPI-2
    		Control
    (R)-TAPI-2 is the isomer of TAPI-2 (HY-100211A). TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP. TAPI-2 blocks the entry of infectious SARS-CoV.
  • HY-139355
    (S)-GS-621763
    		Control
    (S)-GS-621763 is the S-enantiomer of GS-621763 (HY-145119). GS-621763 is an orally active prodrug form of GS-443902 (HY-126303) that inhibits SARS-CoV-2.
  • HY-W076298
    Remdesivir intermediate-1
    		Control
    Remdesivir intermediate-1 is a synthetic intermediate that can be used in the synthesis of Remdesivir (HY-104077).
  • HY-145530
    (S)-Hydroxychloroquine sulfate
    		Control
    (S)-Hydroxychloroquine ((S)-HCQ) sulfate is an isomer of Hydroxychloroquine (HY-W031727). (S)-Hydroxychloroquine sulfate (2.5-20 mg/mL) reduces the rate of insulin degradation in liver homogenates isolated from non-diabetic and diabetic rats. Formulations containing Hydroxychloroquine have been used in the study of malaria, rheumatoid arthritis, and systemic lupus erythematosus.