2. Signaling Pathways
  3. TGF-beta/Smad
  4. TGF-β Receptor
  5. ACVR2A Isoform

ACVR2A

 
Cat. No. Product Name Effect Purity
  • HY-P99355
    Bimagrumab
    		Inhibitor 99.07%
    Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII), with KDs of 1.7 pM and 434 pM for human ActRIIB and ActRIIA, respectively. Bimagrumab can be used for the research of pathological muscle loss and weakness.
  • HY-P99590
    Sotatercept
    		99.61%
    Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions.
Cat. No. Product Name / Synonyms Species Source