2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. VD/VDR
  5. VD/VDR Antagonist

VD/VDR Antagonist

VD/VDR Antagonists (14):

Cat. No. Product Name Effect Purity
  • HY-147337
    MeTC7
    		Antagonist 98.50%
    MeTC7 is a Vitamin-D receptor (VDR) antagonist. MeTC7 has potent VDR inhibition activity with an IC50 value of 2.9 μM. MeTC7 shows good antitumor effects.
  • HY-12407
    ZK168281
    		Antagonist ≥98.0%
    ZK168281 is a 25-carboxylic ester 1α,25(OH)2D3 analog and a pure VDR antagonist with a Kd value of 0.1 nM. ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor.
  • HY-12397
    ZK159222
    		Antagonist
    ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character.
  • HY-52121
    Windaus ketone
    		Antagonist 98.37%
    Windaus ketone is a VD building blocker.
  • HY-B1014
    Acenocoumarol
    		Antagonist 99.87%
    Acenocoumarol is an anticoagulant that functions as a Vitamin K antagonist. Acenocoumarol inhibits MAPK/ERK/JNK signaling pathway, reduces the nuclear translocation of NF-κB p65, activates Akt/GSK3β signaling pathway. Acenocoumarol induces apoptosis in cell A549, arrests cell cycle at S phase.
  • HY-B0325
    Phenindione
    		Antagonist 98.21%
    Phenindione is an anticoagulant and can act as a vitamin K antagonist.
  • HY-A0145
    Phenprocoumon
    		Antagonist 98.02%
    Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.
  • HY-14854
    Tecarfarin
    		Antagonist 98.65%
    Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X. Tecarfarin has the antithrombotic activity .
  • HY-U00017
    Coumetarol
    		Antagonist 99.01%
    Coumetarol (Dicumoxane) is a vitamin K antagonist.
  • HY-14854A
    Tecarfarin sodium
    		Antagonist
    Tecarfarin sodium (ATI-5923 sodium) is a novel orally active non-competitive vitamin K epoxide reductase (VKOR) antagonist, impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X. Tecarfarin sodium has the antithrombotic activity.
  • HY-106561
    Tioclomarol
    		Antagonist
    Tioclomarol, a coumarin anticoagulant, is a vitamin K antagonist.
  • HY-A0145R
    Phenprocoumon (Standard)
    		Antagonist
    Phenprocoumon (Standard) is the analytical standard of Phenprocoumon. This product is intended for research and analytical applications. Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.
  • HY-B0325R
    Phenindione (Standard)
    		Antagonist
    Phenindione (Standard) is the analytical standard of Phenindione. This product is intended for research and analytical applications. 0
  • HY-W013200
    Coumachlor
    		Antagonist
    Coumachlor is an orally active antieoagulant agent. Coumachlor is a vitamin K antagonist.