2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. VEGFR
  5. VEGFR2/KDR/Flk-1 Isoform
  6. VEGFR2/KDR/Flk-1 Antagonist

VEGFR2/KDR/Flk-1 Antagonist

VEGFR2/KDR/Flk-1 Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-P10833
    VGB3
    		Antagonist
    VGB3 is an antagonist peptide of vascular endothelial growth factor receptor 1 (VEGFR1/Flt-1)/VEGFR2/KDR/Flk-1 with antiangiogenic and antitumor effects. VGB3 binds to both VEGFR1/Flt-1 and VEGFR2/KDR/Flk-1, thereby inhibits VEGF-driven proliferation, migration and tube formation of endothelial cells, and tumor growth and metastasis in murine 4T1 mammary carcinoma tumor model.