2. Signaling Pathways
  3. Stem Cell/Wnt
  4. Wnt
  5. Wnt Modulator

Wnt Modulator

Wnt Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-10593
    IQ 1
    		Modulator 99.13%
    IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin-driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP-mediated transcription and preventing conversion to β-catenin/p300-mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion.
  • HY-N7171
    4,4'-Di-O-methylellagic acid
    		Modulator
    4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) can be isolated from the Australian termites. 4,4'-Di-O-methylellagic acid is blue-fluorescent under ultra-violet light. 4,4'-Di-O-methylellagic acid inhibits colon cancer cell proliferation via the wnt signal pathway.