2. Signaling Pathways
  3. Stem Cell/Wnt
  4. YAP
  5. YAP/TAZ Isoform
  6. YAP/TAZ Activator

YAP/TAZ Activator

YAP/TAZ Activator (1):

Cat. No. Product Name Effect Purity
  • HY-147082
    GA-017
    		Activator 98.95%
    GA-017 is a potent and selective LATS1 and LATS2 (large tumor suppressor kinase 1/2) inhibitor, with IC50 values of 4.10 and 3.92 nM, respectively. GA-017 is an activator of cell proliferation. GA-017 promotes YAP/TAZ activation and nuclear translocation. GA-017 promotes cell growth under 3D culture conditions. GA-017 enhances the ex vivo formation of mouse intestinal organoids.