2. Signaling Pathways
  3. Adhesion G Protein-coupled Receptors (AGPCRs)
  4. Adhesion G Protein-coupled Receptors (AGPCRs) Activator

Adhesion G Protein-coupled Receptors (AGPCRs) Activator

Adhesion G Protein-coupled Receptors (AGPCRs) Activator (1):

Cat. No. Product Name Effect Purity
  • HY-16950A
    (E/Z)-4-Hydroxytamoxifen
    		Activator 99.62%
    (E/Z)-4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. (E/Z)-4-Hydroxytamoxifen is a selective estrogen receptor modulator with mixed estrogenic and antiestrogenic activity, which is also an active metabolite of Tamoxifen (HY-13757A). (E/Z)-4-Hydroxytamoxifen is an agonist of the G protein-coupled estrogen receptor (GPER) with relatively low affinity (100-1000 nM). (E/Z)-4-Hydroxytamoxifen is promising for research of cyclical mastalgia, such as breast pain, tenderness, and nodularity.