Antibiotic Inhibitor

Antibiotic Inhibitors (78):

Cat. No.	Product Name	Effect	Purity

HY-126696

Altromycin D	Inhibitor
Altromycin D is a Gram-positive antibiotic.

HY-N7454

Anhydroerythromycin A	Inhibitor
Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.

HY-126559

Ansatrienin A	Inhibitor
Ansatrienin A is an antifungal antibiotic that can be isolated from Streptomyces collinus.

HY-117831

NSC-79887	Inhibitor
NSC-79887 is a nucleoside hydrolase (NH) inhibitor with activity against Bacillus anthracis. NSC-79887 is considered a good candidate inhibitor of nucleoside hydrolases for biological testing and further development. The pharmacokinetic (ADMET) prediction of NSC-79887 showed that all physicochemical parameters were within the acceptable range for human use.

HY-162564

Antibacterial agent 221	Inhibitor
Antibacterial agent 221 (compound 3k) is a potent inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 221 shows significant cytotoxicity against human LO2 and HepG2 cells.

HY-161490

AMOZ/BSA	Inhibitor
AMOZ/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-131152

Leucinostatin (mixture of A&B)	Inhibitor
Leucinostatin (mixture of A&B), the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus, are antibiotics.

HY-B1252B

Cefalonium dihydrate	Inhibitor
Cefalonium dihydrate is a cephalosporin antibiotic. Cefalonium (dihydrate) is effective against Staphylococcus aureus. Cefalonium (dihydrate) has anti-inflammatory and antibacterial activities.

HY-117845

Citreamicin alpha	Inhibitor
Citreamicin alpha (LL-E 19085-alpha) is an antibiotic whose in vitro antimicrobial activity against 429 clinical isolates of Gram-positive cocci has been tested by the agar dilution method. These microorganisms included 313 strains of Staphylococci and 116 strains of Streptococci. The in vitro activity of Citreamicin alpha was compared with that of ampicillin, amoxicillin, ceftriaxone, erythromycin, and vancomycin. For Staphylococci, the MIC values of Citreamicin alpha ranged from 0.12-4.0 μg/ml, and for Streptococcus pyogenes of the genus Streptococcus, it was 0.03-0.12 μg/ml. However, enterococci were relatively resistant, requiring 2.0 μg/ml of the agent to inhibit 64% of the 62 tested strains. The in vitro activity of this antibiotic was much better than that of ampicillin, amoxicillin, ceftriaxone, and erythromycin, but comparable or slightly inferior to that of vancomycin.

HY-W764182

Cephalosporinase,bacillus	Inhibitor
Cephalosporinase, bacillus are enzymes produced by bacillus, inactivated and degrade the ability of the cephalosporin class of antibiotics. Cephalosporins are a class of β-lactam antibiotics that are widely used to treat bacterial infections.

HY-B1369R

Imipenem monohydrate (Standard)	Inhibitor
Imipenem (monohydrate) (Standard) is the analytical standard of Imipenem (monohydrate). This product is intended for research and analytical applications. Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections.

HY-163708

Antibacterial agent	Inhibitor
Antibacterial agent (compound 8b) is a potent antibacterial agent. Antibacterial agent shows robust antibacterial efect on E. coli and S. aureus with IC₅₀s of 64 and 32 µg/mL, respectively.

HY-125706

1233B	Inhibitor
1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94.

HY-144391

Chitin synthase inhibitor 1	Inhibitor
Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor (IC₅₀=0.12 mM). Chitin synthase inhibitor 1 has potent antifungal activity against drug-resistant fungi variants.

HY-122071

Bicyclomycin	Inhibitor
Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa.

HY-126783

Levorin A0	Inhibitor
Levorin A0 is a Levorin component. Levorin is an aromatic polyene (heptaene) antibiotic with high antifungal activity.

HY-122146

Bactobolin B	Inhibitor
Bactobolin B (Alanylbactobolin) is a chlorine-containing antibiotic with antitumor activities.

HY-B1252R

Cefalonium (Standard)	Inhibitor
Cefalonium (Standard) is the analytical standard of Cefalonium. This product is intended for research and analytical applications. Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci.

HY-N13878

Anguinomycin B	Inhibitor
Anguinomycin B is an antitumor antibiotic that shows highly cytotoxic to murine P388 leukemia cells.

HY-105284A

Sulopenem sodium	Inhibitor
Sulopenem (sodium)(CP-70429 (sodium)) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia.

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