2. Signaling Pathways
  3. Autophagy
  4. Atg8/LC3
  5. Atg8/LC3 Modulator

Atg8/LC3 Modulator

Atg8/LC3 Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-N6796
    Manumycin A
    		Modulator 99.27%
    Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 (TrxR-1). Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF α, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion.