2. Signaling Pathways
  3. Autophagy
  4. Beclin1
  5. Beclin1 Modulator

Beclin1 Modulator

Beclin1 Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-134050
    Apostatin-1
    		Modulator 99.24%
    Apostatin-1 (Apt-1) is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N (KD=2.17 μM), disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, α-synuclein, or huntingtin.