2. Signaling Pathways
  3. Claudin
  4. Claudin Inhibitor

Claudin Inhibitor

Claudin Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-W014507
    9,10-Phenanthrenequinone
    		Inhibitor 99.95%
    9,10-Phenanthrenequinone is an inhibitor of claudin-5/CLDN5 that induces apoptosis via a NO synthase/ROS-dependent mechanism. 9,10-Phenanthrenequinone also promotes endothelial barrier dysfunction by promoting caspase activation and DNA fragmentation, and reducing CLDN5 expression and proteasomal proteolysis.
  • HY-171152
    NSC 357754
    		Inhibitor
    NSC 357754 is an inhibitor of Claudin. NSC 357754 can increase the transepithelial electrical resistance of cells and reduce the permeability of specific cations. NSC 357754 can be used in the research of intestinal diseases mediated by Claudin-2 and/or Claudin-15.