2. Signaling Pathways
  3. Anti-infection
  4. EBV

EBV

Epstein-Barr Virus

Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a member of the herpes virus family. It is one of the most common human viruses. EBV is found all over the world. Most people get infected with EBV at some point in their lives. EBV spreads most commonly through bodily fluids, primarily saliva. Primary EBV infection is usually asymptomatic and for many occurs during childhood, but when it occurs in adolescence or adulthood, 30%–50% cases manifest clinically as infectious mononucleosis (IM). EBV also cause infectious mononucleosis (IM), Burkitt lymphoma (BL), nasopharyngeal carcinoma (NPC), Hodgkin’s disease, and other illnesses. Many people become infected with EBV in childhood. EBV infections in children usually do not cause symptoms, or the symptoms are not distinguishable from other mild, brief childhood illnesses.

EBV Related Products (40):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P1890
    CEF14, EBV Rta Protein (28-37)
    CEF14, EBV Rta Protein (28-37) is the HLA A24-restricted epitope from Epstein-Barr Virus Rta protein (28-37).
    CEF14, EBV Rta Protein (28-37)
  • HY-105070
    Eritoran
    		Inhibitor
    Eritoran （E5564 free base） is a Toll-like receptor 4 (TLR4) antagonist. Eritoran protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran decreases the level of granulocytosis, may alleviate the severity of the "cytokine storm". Eritoran inhibits pathogenesis of filovirus infection. Eritoran has anti-inflammatory activity.
    Eritoran
  • HY-N11009
    11-Oxomogroside II A1
    		Inhibitor
    11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.
    11-Oxomogroside II A1
  • HY-N6643
    Rubropunctamine
    Rubropunctamine is a redMonascus pigment. Not only Rubropunctamine exerts antibiotic action against bacteria but also against some yeast and filamentous fungi strains. Rubropunctamine has potential embryotoxicity and teratogenicity.
    Rubropunctamine
  • HY-130789
    Cimigenol-3-one
    		Inhibitor
    Cimigenol-3-one inhibits Epstein-Barr virus early antigen (EBV-EA) activation.
    Cimigenol-3-one
  • HY-N2006R
    Ganoderic acid B (Standard)
    Ganoderic acid B (Standard) is the analytical standard of Ganoderic acid B. This product is intended for research and analytical applications. Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM).
    Ganoderic acid B (Standard)
  • HY-P5475
    BMLF1 (280–288)
    BMLF1 (280–288) is a biological active peptide. (HLA A2.1-restricted epitope from Epstein-Barr Virus lytic protein BMLF1 (280-288).)
    BMLF1 (280–288)
  • HY-P1911
    CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156)
    CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 corresponding to amino acids 148-156 of the BRLF1 protein. BRLF1 is a transcriptional activator that binds directly to a GC-rich motif present in some Epstein-Barr virus (EBV) lytic gene promoters.
    CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156)
  • HY-N3254
    Minumicrolin
    Minumicrolin is a plant growth inhibitor. Minumicrolin can be isolated from Murraya paniculata. Minumicrolin inhibits Epstein-Barr virus early antigen (EBV-EA) activation.
    Minumicrolin
  • HY-148170
    L-I-OddU
    		Inhibitor
    L-I-OddU, a L-5'-halo- dioxolane nucleoside analogue, is a potent and selective anti-Epstein-Barr virus (EBV) agent with an EC50 value of 0.03μM. L-I-OddU has low cytotoxicity with a CC50 value of 1000 nM. L-I-OddU has antiviral activity by suppressing replicative EBV DNA and viral protein synthesis.
    L-I-OddU
  • HY-N7015R
    Zerumbone (Standard)
    Zerumbone (Standard) is the analytical standard of Zerumbone. This product is intended for research and analytical applications. Zerumbone is an orally active natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet. Zerumbone has anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity.
    Zerumbone (Standard)
  • HY-P1920
    CEF19, Epstein-Barr Virus latent NA-3A (458-466)
    CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain). CEF19, Epstein-Barr Virus latent NA-3A (458-466) can significantly affect cytotoxic T-lymphocyte (CTL) recognition.
    CEF19, Epstein-Barr Virus latent NA-3A (458-466)
  • HY-105098
    Lobucavir
    		Inhibitor
    Lobucavir (BMS-180194; SQ 34514), a nucleoside analogue, is an antiviral agent. Lobucavir shows a broad spectrum of activity against HBV, HIV/AIDS, and α, β, and γ herpes viruses including CMV, herpes-simplex, varicella-zoster, and Epstein-Barr virus.
    Lobucavir
  • HY-N8459
    α-Cembrenediol
    		Inhibitor
    α-Cembrenediol is a potent inhibitor of EBV.α-Cembrenediol inhibits the early antigen of the Epstein-Bar virus. α-Cembrenediol also has anti-tumour activity.
    α-Cembrenediol
  • HY-N6033
    Ferruginol
    Ferruginol ((+)-Ferruginol), a natural diterpenoid, is an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). Ferruginol inhibits the growth of thyroid cancer cells through the induction of mitochondrial apoptosis. Ferruginol has antitumor, cardioprotective, antioxidant, gastroprotective, and neuroprotective activities.
    Ferruginol
  • HY-P5482
    Epstein-barr virus BRLF1 (134-142)
    Epstein-barr virus BRLF1 (134-142) is a biological active peptide. (HLA-A11 restricted epitope from Epstein-Barr Virus BRLF1 (134-142).)
    Epstein-barr virus BRLF1 (134-142)
  • HY-N7563
    α-Toxicarol
    		Inhibitor
    α-Toxicarol is a potent inhibitor of EBV.α-Toxicarol significantly inhibits mouse skin tumor in vivo. α-Toxicarol inhibits the TPA-induced EBV-EA activation.
    α-Toxicarol
  • HY-16305R
    Maribavir (Standard)
    Maribavir (Standard) is the analytical standard of Maribavir. This product is intended for research and analytical applications. Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus (EBV).
    Maribavir (Standard)
  • HY-W725179
    VK-2019
    		Inhibitor
    VK-2019 is an oral active, selective EBNA1((Epstein-Barr Nuclear Antigen 1) inhibitor and can be used for study of EBV-associated carcinomas.
    VK-2019
  • HY-U00224
    BRL44385
    BRL44385 is a potent and selective inhibitor of the replication of herpes simplex virus types 1 and 2 (HSV-1 and HSV2), varicella zoster virus (VZV) and Epstein-Barr virus (EBV).
    BRL44385