2. Signaling Pathways
  3. Immunology/Inflammation
  4. Fc Receptor (FcR)
  5. Fc Receptor (FcR) Inhibitor

Fc Receptor (FcR) Inhibitor

Fc Receptor (FcR) Inhibitors (8):

Cat. No. Product Name Effect Purity
  • HY-P99009
    Batoclimab
    		Inhibitor 99.89%
    Batoclimab is a human anti-FcRn monoclonal antibody. Batoclimab can be used for the research of autoimmune diseases mediated by pathogenic IgG antibodies.
  • HY-P990676
    VIB-9600
    		Inhibitor 99.41%
    VIB-9600 is a humanized antibody expressed in CHO cells, targeting FcgR2a/CD32a. VIB-9600 has a huIgG1 type heavy chain and huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for VIB-9600 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
  • HY-P991086
    MGD010
    		Inhibitor
    MGD010 is a bispecific CD32B (FcγRIIb) and CD79B antibody. MGD010 inhibits activated B-cells by delivering a negative signal via simultaneous co-ligation of CD32B (FcγRIIb), with the BCR component, CD79B. MGD010 has the potential for the study of autoimmune disorders.
  • HY-P991074
    GMA-161
    		Inhibitor
    GMA-161 is a humanized IgG1 antibody that targets Fcγ receptor III (CD16). GMA-161 has the potential for the study of autoimmune disorders. The isotype control for GMA-161 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
  • HY-P990413
    Anti-Fc gamma R1 Antibody
    		Inhibitor
    The Anti-Fc gamma R1 Antibody is a human-derived antibody expressed in CHO, targeting Fc gamma R1. The Anti-Fc gamma R1 Antibody features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. For the isotype control of the Anti-Fc gamma R1 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
  • HY-145775
    hIgG-hFc receptor-IN-1
    		Inhibitor
    hIgG–hFc receptor-IN-1 (comp 66) is a human immunoglobulin G–human neonatal Fc receptor (hIgG–hFcRn) protein-protein interaction inhibitor, with an IC50 of 2 μM .
  • HY-158316
    BTL-MK
    		Inhibitor
    BTL-MK (Compound 19) an orally active antiallergic agent, that inhibits degranulation of mast cells with an IC50 of 6.7 μM, through binding to the inhibitory receptor FcγRIIB. BTL-MK improves the metaboilic stability in human liver microsomes. BTL-MK ameliorates the allergic response in Ovalbumins (HY-W250978)-induced food allergy mice model. BTL-MK exhibits a good pharmacokinetic character with metabolic stability.
  • HY-P990244
    Anti-Rat FcRn heavy chain heterodimers Antibody (2G3)
    		Inhibitor
    Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) is a mouse-derived IgG1 type antibody inhibitor, targeting to rat FcRn heavy chain heterodimers.