2. Signaling Pathways
  3. GPCR/G Protein
  4. GLP Receptor
  5. GLP Receptor Inhibitor

GLP Receptor Inhibitor

GLP Receptor Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-P990047
    Maridebart
    		Inhibitor
    Maridebart is a human immunoglobulin G1-kappa, anti-GIPR (gastric inhibitory polypeptide receptor) monoclonal antibody.
  • HY-E70397
    Dipeptidyl peptidase IV
    		Inhibitor
    Dipeptidyl peptidase IV (DPP-IV) is a protease that inactivates insulin stimulating hormones such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulin-like polypeptide (GIP). Dipeptidyl peptidase IV can be used as a binding protein and ligand for various extracellular molecules. Dipeptidyl peptidase IV can be used in diabetes research.
  • HY-114628
    MS012
    		Inhibitor
    MS012 is a selective GLP inhibitor (IC50=7 nM). MS012 can be used in research of GLP dysregulation, including cancer, inflammatory diseases, and neuroregenerative disorders.
  • HY-155020
    Antitumor agent-101
    		Inhibitor
    Antitumor agent-101 is a selective covalent inhibitor of lysine methyltransferases G9a/GLP, with IC50s of 8.5 nM and 5.5 nM for G9a and GLP, respectively. Antitumor agent-101 shows antitumor efficacy in the PANC-1 xenograft model.