2. Signaling Pathways
  3. GPCR/G Protein
  4. GPR35
  5. GPR35 Activator

GPR35 Activator

GPR35 Activators (2):

Cat. No. Product Name Effect Purity
  • HY-W018158
    DHICA
    		Activator
    DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an intermediate in melanin synthesis and a component of true black pigment, and it’s also a moderately potent GPR35 agonist. DHICA shows an ability to stimulate β-arrestin translocation signaling with an EC50 value of 23.2 μM in the U2OS cell line. DHICA plays a significant role in promoting and protecting against DNA damage.
  • HY-169302
    GPR35 activator-1
    		Activator
    GPR35 activator-1 (example 5) is a potent GPR35 activator with a Ki of 0.08 nM for human GPR35.