2. Signaling Pathways
  3. GPCR/G Protein
  4. GPR68
  5. GPR68 Modulator

GPR68 Modulator

GPR68 Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-110279
    Ogerin
    		Modulator 99.58%
    Ogerin is a selective GPR68 positive aliasing modulator (PAM) (pEC50=6.83) with a moderate antagonistic effect on A2A (Ki=220 nM). Ogerin inhibits the fear conditioning reflex in mice and also inhibits TGF-β-induced myofibroblast differentiation of fibroblasts from multiple organ systems. Ogerin can be used in the studies of fibrotic diseases and neurological disorders.