2. Signaling Pathways
  3. Immunology/Inflammation
  4. IKZF Family
  5. IKZF4 Isoform

IKZF4

 

IKZF4 Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-144998
    NVP-DKY709
    		Degrader 98.86%
    NVP-DKY709 is an orally active and selective IKZF2 molecular glue degrader with the Dmax and DC50 of 53% and 4 nM, respectively. In addition, NVP-DKY709 can degrade IKZF4 (DC50: 13 nM) and SALL4 (DC50: 2 nM). NVP-DKY709 exerts anti-tumor activity by binding with CRBN to change conformation and recruit and degrade IKZF2.