2. Signaling Pathways
  3. Metabolic Enzyme/Protease
    PI3K/Akt/mTOR
  4. IPK Superfamily
  5. IPK Superfamily Inhibitor

IPK Superfamily Inhibitor

IPK Superfamily Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-150607
    UNC7467
    		Inhibitor 98.07%
    UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. UNC7467 reduces levels of inositol pyrophosphates. UNC7467 can be used for obesity research.
  • HY-110079
    TNP
    		Inhibitor 99.29%
    TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 µM and 10.2 µM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes.
  • HY-153530
    LI-2242
    		Inhibitor 98.95%
    LI-2242 is an inositol hexakisphosphate kinase (IP6K) inhibitor. LI-2242 has inhibition effect for IP6K1, IP6K2, IP6K3 and IPMK with IC50 values of 31 nM, 42 nM, 8.7 nM and 1944 nM, respectively. LI-2242 can be used for thew research of type II diabetes, obesity, metabolic complications, venous thrombosis, and psychiatric disorders.
  • HY-122706A
    IP6K2-IN-2
    		Inhibitor 98.85%
    IP6K2-IN-2 (Compound 6) is an IP6K2 inhibitor, with IC50 values of 0.58 μM (IP6K2), 0.86 μM (IP6K1) and 3.08 μM (IP6K3). IP6K2-IN-2 can be used in research of obesity.
  • HY-162821
    LI-3948
    		Inhibitor
    IP6K-IN-2 (compound 29c) is an orally bioavailable and blood-brain barrier permeable IP6K inhibitor (IC50: 15.8 nM) that can be used in the study of central nervous system diseases.
  • HY-162016
    IP6K-IN-1
    		Inhibitor
    IP6K-IN-1 (compound 24) is a potent and selective inhibitor of IP6K with an IC50 of 0.896 μM. IP6K-IN-1 can used in study metabolic disease.
  • HY-161032
    IP6K2-IN-1
    		Inhibitor
    IP6K2-IN-1 (Compd 20s) is a selective IP6K2 inhibitor, with an ICIC50 value of 0.55 μM.