2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. KMO
  5. KMO Inhibitor

KMO Inhibitor

KMO Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-112179
    GSK180
    		Inhibitor 99.04%
    GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway. GSK180 rapidly changes levels of kynurenine pathway metabolites, and acts as a useful tool to probe the therapeutic potential of KMO inhibition.