2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. NEKs
  5. NEKs Isoform

NEKs

 

NEKs Related Products (4):

Cat. No. Product Name Effect Purity
  • HY-159520
    Ofirnoflastum
    		Inhibitor
    Ofirnoflastum (Ofirnoflast) is a serine/ threonine-protein kinase Nek7 inhibitor, with anti inflammatory effect.
  • HY-168737
    NEK7-IN-2
    		Inhibitor
    NEK7-IN-2 (compound 23) is a potent inhibitor of NLRP3-NEK7 interaction. NEK7-IN-2 can enhance the thermal stability of NEK7 and regulatie NLRP3 inflammasome assembly. NEK7-IN-2 inhibits IL-1β releases.
  • HY-117398
    HCI-2184
    		Inhibitor
    HCI-2184 is a Nek2 inhibitor with an IC50 of 39.90 nM. HCI-2184 significantly increases the effectiveness of Bortezomib (HY-10227) in inhibiting proteasome activity.
  • HY-169933
    NEK7-IN-1
    		Inhibitor
    NEK7-IN-1 (Compound I-15) is the inhibitor for NIMA-related kinase 7 NEK7 with IC50 <100 nM. NEK7-IN-1 inhibits the IL-1β release with IC50 <50 nM.