2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. PEPCK
  5. PEPCK Inhibitor

PEPCK Inhibitor

PEPCK Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-128923
    SKF-34288 hydrochloride
    		Inhibitor
    SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (Ki: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides.
  • HY-111896
    7-Methoxyrosmanol
    		Inhibitor 98.56%
    7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters.
  • HY-N3720
    Demethoxycapillarisin
    		Inhibitor
    Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production.