2. Signaling Pathways
  3. GPCR/G Protein
  4. Platelet-activating Factor Receptor (PAFR)
  5. Platelet-activating Factor Receptor (PAFR) Agonist

Platelet-activating Factor Receptor (PAFR) Agonist

Platelet-activating Factor Receptor (PAFR) Agonists (4):

Cat. No. Product Name Effect Purity
  • HY-W040221
    Butanoyl PAF
    		Agonist
    Butanoyl PAF, a compound closely related to Azelaoyl PC (HY-134154), maintains over 10% of the agonist potency of platelet-activating factor (PAF). Butanoyl PAF's concentration in oxidized low-density lipoprotein surpasses that of enzymatically generated PAF by more than 100-fold.
  • HY-137257
    Carbamyl-PAF
    		Agonist ≥99.0%
    Carbamyl-PAF is an analog and agonist of platelet-activating factor (PAF). Carbamyl-PAF is not significantly metabolized by Raji lymphoblasts at 37°C, making it a useful tool for inflammation research. .
  • HY-121394
    L-659,989
    		Agonist
    L-659,989 is an orally active, extremely potent, selective and competitive platelet activating factor (PAF) receptor antagonist.
  • HY-126551
    Butenoyl-PAF
    		Agonist
    Butenoyl-PAF is a phospholipid analog of platelet activating factor (PAF-like) that is generated in oxidized low-density lipoprotein (DLDR). Butenoyl-PAF can activate cells that express human PAF receptors, such as neutrophils, monocytes, and platelets, and it stimulates an increase in intracellular calcium ion concentration.