2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Pyruvate Carboxylase (PC)
  5. Pyruvate Carboxylase (PC) Inhibitor

Pyruvate Carboxylase (PC) Inhibitor

Pyruvate Carboxylase (PC) Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-142870
    ZY-444
    		Inhibitor 98.70%
    ZY-444 is a small molecule that suppresses breast cancer progression by targeting pyruvate carboxylase.
  • HY-161680
    Pyruvate Carboxylase-IN-4
    		Inhibitor
    Pyruvate Carboxylase-IN-4 (Compd 8V) is a potent and competitive Pyruvate Carboxylase inhibitor with an IC50 of 4.3 μM.
  • HY-163771
    Pyruvate Carboxylase-IN-5
    		Inhibitor
    Pyruvate Carboxylase-IN-5 (compound 6m) is a pyruvate carboxylase inhibitor with high selectivity and permeability. Pyruvate carboxylase is a mitochondrial enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, a process that plays an important role in maintaining steady-state levels of Krebs cycle intermediates, which are precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose.