2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Separase
  5. Separase Inhibitor

Separase Inhibitor

Separase Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-117522
    Sepin-1
    		Inhibitor
    Sepin-1 is a potent separase inhibitor with an IC50 value of 14.8 µM. Sepin-1 inhibits cell proliferation, migration and wound healing. Sepin-1 decreases the expression of FoxM1 protein and mRNA level. Sepin-1 shows anti-tumor activity.
  • HY-138084
    SIC5-6
    		Inhibitor 99.82%
    SIC5-6 is a potent Separase inhibitor. Separase, a large cysteine protease, involves in chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, spindle stabilization and elongation. Separase is highly overexpressed in many solid cancers, serves as an attractive chemotherapeutic target.