2. Signaling Pathways
  3. Epigenetics
  4. SF3B1
  5. SF3B1 Modulator

SF3B1 Modulator

SF3B1 Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-170368
    3′-Me Meayamycin D
    		Modulator
    3’-Me Meayamycin D is a splicing modulator on SF3B1 and PHF5A, that affects the pre-mRNA splicing process, and downregulates the MCL-1 expression. 3’-Me Meayamycin D inhibits the proliferation of cancer cell HCT116, SW48, A549, DMS53 and DMS114 with GI50 of 4.6-7.2 nM. 3’-Me Meayamycin D exhibits good plasma stability in mice with a halt-life of 16 h.