2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Sialyltransferase
  5. Sialyltransferase Inhibitor

Sialyltransferase Inhibitor

Sialyltransferase Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-173496
    ST6GAL1-IN-1
    		Inhibitor
    ST6GAL1-IN-1 (compound 4e) is a potent and selective ST6GAL1 inhibitor with an IC50 of 20.0 μM. ST6GAL1-IN-1 exhibits antimetastatic activity and effectively inhibiting MDA-MB-231 cell migration. ST6GAL1-IN-1 also suppresses tumor growth and metastasis in vivo.
  • HY-P991369
    EBU-141
    		Inhibitor
    EBU-141 is a human monoclonal antibody (mAb) targeting CD75/ST6GAL1. EBU-141 can be used in B-cell lymphoma and multiple myeloma research.
  • HY-163548
    SPP-002
    		Inhibitor ≥98.0%
    SPP-002 is a sulfate analogue that acts as a potential Sialyltransferase (ST) inhibitor. SPP-002 selectively inhibits n-glycosialylation with inhibition at least an order of magnitude greater than that of unmodified parental cholic acid (LCA). SPP-002 reduces tumor cell migration and invasion by inhibiting the integrin /FAK/Paxillin signaling pathway. SPP-002 can be used in the study of tumor metastasis.