2. Signaling Pathways
  3. SWI/SNF Complex
  4. SWI/SNF Complex Inhibitor

SWI/SNF Complex Inhibitor

SWI/SNF Complex Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-161886
    SMARCA2-IN-7
    		Inhibitor
    SMARCA2-IN-7 (compound 12), a dual inhibitor of BRM and BRG1 (IC50 < 0.005 for both), has an anti-tumor proliferation effect that inhibits BRG1-deleted SKMEL5 tumor proliferation with a cell proliferation activity AAC50 of 13 nM in SKMEL5. The cell proliferation activity AAC50 of KRT880 in H1299 cells was 42 nM.