2. Signaling Pathways
  3. Neuronal Signaling
  4. Tau Protein
  5. Tau Protein Ligand

Tau Protein Ligand

Tau Protein Ligands (3):

Cat. No. Product Name Effect Purity
  • HY-101186
    MK-6240
    		Ligand 99.60%
    MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs.
  • HY-138679
    Aberrant tau degrader 2
    		Ligand
    Aberrant tau degrader 2 (Compound 4-12) is the degrader for tau protein and can be used as target protein ligand for synthesis of PROTAC degrader C004019 (HY-138669).
  • HY-W338446
    BF-170
    		Ligand
    BF-170 is a selective tau fibril binding agent with an EC50 of 221 nM. It exhibits good blood-brain barrier permeability, and after intravenous injection in mice, the concentration in brain tissue reaches 9.1% ID/g within 2 minutes (with a brain clearance rate of 0.25% ID/g after 30 minutes). BF-170 can be used as a probe for tau protein pathology imaging in Alzheimer's disease (AD). It plays an important role in early-stage AD research and holds potential for imaging studies of tau-related neurodegenerative diseases.